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The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation

The efficacy of current antimalarial drugs is threatened by reduced susceptibility of Plasmodium falciparum to artemisinin, associated with mutations in pfkelch13. Another gene with variants known to modulate the response to artemisinin encodes the μ subunit of the AP-2 adaptin trafficking complex....

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Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Henrici, Ryan C., Edwards, Rachel L., Zoltner, Martin, van Schalkwyk, Donelly A., Hart, Melissa N., Mohring, Franziska, Moon, Robert W., Nofal, Stephanie D., Patel, Avnish, Flueck, Christian, Baker, David A., Odom John, Audrey R., Field, Mark C., Sutherland, Colin J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042695/
https://ncbi.nlm.nih.gov/pubmed/32098816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02918-19
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