The Mu Subunit of Plasmodium falciparum Clathrin-Associated Adaptor Protein 2 Modulates In Vitro Parasite Response to Artemisinin and Quinine

The emergence of drug-resistant parasites is a serious threat faced by malaria control programs. Understanding the genetic basis of resistance is critical to the success of treatment and intervention strategies. A novel locus associated with antimalarial resistance, ap2-mu (encoding the mu chain of...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Henriques, Gisela, van Schalkwyk, Donelly A., Burrow, Rebekah, Warhurst, David C., Thompson, Eloise, Baker, David A., Fidock, David A., Hallett, Rachel, Flueck, Christian, Sutherland, Colin J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394773/
https://ncbi.nlm.nih.gov/pubmed/25691625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04067-14
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