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Ca(2+) signalling in fibroblasts and the therapeutic potential of K(Ca)3.1 channel blockers in fibrotic diseases

The role of Ca(2+) signalling in fibroblasts is of great interest in fibrosis‐related diseases. Intracellular free Ca(2+) ([Ca(2+)](i)) is a ubiquitous secondary messenger, regulating a number of cellular functions such as secretion, metabolism, differentiation, proliferation and contraction. The in...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Roach, Katy M., Bradding, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042111/
https://ncbi.nlm.nih.gov/pubmed/31758702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14939
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