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Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells
G protein-coupled receptors (GPCRs) signal through allostery, and it is increasingly clear that chemically distinct agonists can produce different receptor-based effects. It has been proposed that agonists selectively promote receptors to recruit one cellular interacting partner over another, introd...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7041944/ https://ncbi.nlm.nih.gov/pubmed/32096468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54208 |
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