A genetically encoded biosensor reveals location bias of opioid drug action

Opioid receptors (ORs) precisely modulate behavior when activated by native peptide ligands but distort behaviors to produce pathology when activated by non-peptide drugs. A fundamental question is how drugs differ from peptides in their actions on target neurons. Here we show that drugs differ in t...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Neuron
Autori principali: Stoeber, Miriam, Jullié, Damien, Lobingier, Braden T., Laeremans, Toon, Steyaert, Jan, Schiller, Peter W., Manglik, Aashish, von Zastrow, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481295/
https://ncbi.nlm.nih.gov/pubmed/29754753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.04.021
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi