Uric acid induces stress resistance and extends the life span through activating the stress response factor DAF-16/FOXO and SKN-1/NRF2

Uric acid is a common metabolite found in mammals’ serum. Recently, several metabolites have been identified that modulate aging, and uric acid levels are positively correlated with mammals’ lifespan. However, the molecular mechanisms underlying this are largely undefined. Here we show that uric aci...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Wan, Qin-Li, Fu, Xiaodie, Dai, Wenyu, Yang, Jing, Luo, Zhenhuan, Meng, Xiao, Liu, Xiao, Zhong, Ruowei, Yang, Hengwen, Zhou, Qinghua
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041755/
https://ncbi.nlm.nih.gov/pubmed/32074508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102781
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