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Cyanobacterial pigment protein allophycocyanin exhibits longevity and reduces Aβ-mediated paralysis in C. elegans: complicity of FOXO and NRF2 ortholog DAF-16 and SKN-1

The allophycocyanin (APC) protein purified from Phormidium sp. A09DM was investigated for its in vivo antioxidant and anti-aging potential in Caenorhabditis elegans. An increased mean lifespan of APC-treated (100 μg/ml) worms (wild type) were observed from 16 ± 0.2 days (control) to 20 ± 0.1 days (t...

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Bibliografiske detaljer
Udgivet i:3 Biotech
Main Authors: Chaubey, Mukesh Ghanshyam, Patel, Stuti Nareshkumar, Rastogi, Rajesh Prasad, Madamwar, Datta, Singh, Niraj Kumar
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338320/
https://ncbi.nlm.nih.gov/pubmed/32656065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-020-02314-1
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