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Role of endolysosomes and pH in the pathogenesis and treatment of glioblastoma

BACKGROUND: Glioblastoma multiforme (GBM) is a Grade IV astrocytoma with an aggressive disease course and a uniformly poor prognosis. Pathologically, GBM is characterized by rapid development of primary tumors, diffuse infiltration into the brain parenchyma, and robust angiogenesis. The treatment op...

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Detalhes bibliográficos
Publicado no:Cancer Rep (Hoboken)
Main Authors: Halcrow, Peter, Datta, Gaurav, Ohm, Joyce E., Soliman, Mahmoud L., Chen, Xuesong, Geiger, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039640/
https://ncbi.nlm.nih.gov/pubmed/32095788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1177
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