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Role of endolysosomes and cholesterol in the pathogenesis of Alzheimer’s disease: Insights into why statins might not provide clinical benefit
Altered cholesterol homeostasis in general and increased levels of low-density lipoprotein (LDL) cholesterol specifically is a robust risk factor for the pathogenesis of sporadic Alzheimer’s disease (AD). Because of this, the family of drugs known as statins have been tried extensively to lower chol...
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| Publicado no: | Austin J Pharmacol Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387891/ https://ncbi.nlm.nih.gov/pubmed/25859562 |
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