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Role of endolysosomes and cholesterol in the pathogenesis of Alzheimer’s disease: Insights into why statins might not provide clinical benefit

Altered cholesterol homeostasis in general and increased levels of low-density lipoprotein (LDL) cholesterol specifically is a robust risk factor for the pathogenesis of sporadic Alzheimer’s disease (AD). Because of this, the family of drugs known as statins have been tried extensively to lower chol...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Austin J Pharmacol Ther
मुख्य लेखकों: Chen, Xuesong, Hui, Liang, Geiger, Jonathan D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387891/
https://ncbi.nlm.nih.gov/pubmed/25859562
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