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Importance of measuring endolysosome, cytosolic, and extracellular pH in understanding the pathogenesis of and possible treatments for glioblastoma multiforme

BACKGROUND: Glioblastoma multiforme (GBM) is a very aggressive form of brain cancer that carries with it a tragically poor prognosis. As with many other forms of cancer, the extracellular environment near GBM tumors is acidified and is relevant to the pathogenesis of GBM because decreased pH promote...

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Detalhes bibliográficos
Publicado no:Cancer Rep (Hoboken)
Main Authors: Halcrow, Peter W., Khan, Nabab, Datta, Gaurav, Ohm, Joyce E., Chen, Xuesong, Geiger, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983952/
https://ncbi.nlm.nih.gov/pubmed/31989117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1193
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