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HP1 reshapes the nucleosome core to promote phase separation of heterochromatin

Heterochromatin impacts genome function at multiple scales. It enables heritable gene repression, maintains chromosome integrity and provides mechanical rigidity to the nucleus(1,2). It has been proposed that these diverse functions arise in part from compaction of the underlying chromatin. A major...

詳細記述

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書誌詳細
出版年:Nature
主要な著者: Sanulli, S., Trnka, MJ., Dharmarajan, V., Tibble, RW., Pascal, BD., Burlingame, AL., Griffin, PR., Gross, JD., Narlikar, GJ.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039410/
https://ncbi.nlm.nih.gov/pubmed/31618757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1669-2
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