Ancient Use of Ig Variable Domains Contributes Significantly to the TCRδ Repertoire

The loci encoding B and T cell Ag receptors are generally distinct in commonly studied mammals, with each receptor’s gene segments limited to intralocus, cis chromosomal rearrangements. The nurse shark (Ginglymostoma cirratum) represents the oldest vertebrate class, the cartilaginous fish, with adap...

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Publicat a:J Immunol
Autors principals: Deiss, Thaddeus C., Breaux, Breanna, Ott, Jeannine A., Daniel, Rebecca A., Chen, Patricia L., Castro, Caitlin D., Ohta, Yuko, Flajnik, Martin F., Criscitiello, Michael F.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039070/
https://ncbi.nlm.nih.gov/pubmed/31341077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900369
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