טוען...
Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites
Imbalance in the level of the pyrimidine degradation products dihydrouracil and dihydrothymine is associated with cellular transformation and cancer progression. Dihydropyrimidines are degraded by dihydropyrimidinase (DHP), a zinc metalloenzyme that is upregulated in solid tumors but not in the corr...
שמור ב:
| הוצא לאור ב: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7038975/ https://ncbi.nlm.nih.gov/pubmed/31853544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1162 |
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