Tryptophan Trimers and Tetramers Inhibit Dengue and Zika Virus Replication by Interfering with Viral Attachment Processes

Here, we report a class of tryptophan trimers and tetramers that inhibit (at low micromolar range) dengue and Zika virus infection in vitro. These compounds (AL family) have three or four peripheral tryptophan moieties directly linked to a central scaffold through their amino groups; thus, their car...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Fikatas, Antonios, Vervaeke, Peter, Martínez-Gualda, Belén, Martí-Marí, Olaia, Noppen, Sam, Meyen, Eef, Camarasa, María-José, San-Félix, Ana, Pannecouque, Christophe, Schols, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038274/
https://ncbi.nlm.nih.gov/pubmed/31932383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02130-19
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