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Computer-Aided Drug Design of β-Secretase, γ-Secretase and Anti-Tau Inhibitors for the Discovery of Novel Alzheimer’s Therapeutics

Aging-associated neurodegenerative diseases, which are characterized by progressive neuronal death and synapses loss in human brain, are rapidly growing affecting millions of people globally. Alzheimer’s is the most common neurodegenerative disease and it can be caused by genetic and environmental r...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mouchlis, Varnavas D., Melagraki, Georgia, Zacharia, Lefteris C., Afantitis, Antreas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038192/
https://ncbi.nlm.nih.gov/pubmed/31973122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030703
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