Dystonia: Sparse Synapses for D2 Receptors in Striatum of a DYT1 Knock-out Mouse Model

Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse model. Adult control Tor1a+/+ and mutant Tor1a...

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Publicat a:Int J Mol Sci
Autors principals: D’Angelo, Vincenza, Paldino, Emanuela, Cardarelli, Silvia, Sorge, Roberto, Fusco, Francesca Romana, Biagioni, Stefano, Mercuri, Nicola Biagio, Giorgi, Mauro, Sancesario, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037849/
https://ncbi.nlm.nih.gov/pubmed/32041188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21031073
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