Tumor-induced peripheral immunosuppression promotes brain metastasis in patients with non-small cell lung cancer

INTRODUCTION: Brain metastases are a significant source of morbidity and mortality for patients with lung cancer. Lung cancer can induce local and systemic immunosuppression, promoting tumor growth and dissemination. One mechanism of immunosuppression is tumor-induced expansion of programmed death-l...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Li, Yuping D., Lamano, Jonathan B., Lamano, Jason B., Quaggin-Smith, Jessica, Veliceasa, Dorina, Kaur, Gurvinder, Biyashev, Dauren, Unruh, Dusten, Bloch, Orin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037587/
https://ncbi.nlm.nih.gov/pubmed/31489465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02384-y
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