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Effects of interleukin-2 in immunostimulation and immunosuppression

Historically, interleukin-2 (IL-2) was first described as an immunostimulatory factor that supports the expansion of activated effector T cells. A layer of sophistication arose when regulatory CD4(+) T lymphocytes (Tregs) were shown to require IL-2 for their development, homeostasis, and immunosuppr...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Pol, Jonathan G., Caudana, Pamela, Paillet, Juliette, Piaggio, Eliane, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037245/
https://ncbi.nlm.nih.gov/pubmed/31611250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191247
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