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PERK-Mediated eIF2α Phosphorylation Contributes to The Protection of Dopaminergic Neurons from Chronic Heat Stress in Drosophila

Environmental high-temperature heat exposure is linked to physiological stress such as disturbed protein homeostasis caused by endoplasmic reticulum (ER) stress. Abnormal proteostasis in neuronal cells is a common pathological factor of Parkinson’s disease (PD). Chronic heat stress is thought to ind...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Elvira, Rosalie, Cha, Sun Joo, Noh, Gyeong-Mu, Kim, Kiyoung, Han, Jaeseok
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037073/
https://ncbi.nlm.nih.gov/pubmed/32013014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030845
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