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Expression and Clinical Significance of PERK and Phosphorylated EIF2α in Pancreatic Ductal Adenocarcinoma
OBJECTIVE: Endoplasmic reticulum (ER) stress and subsequent phosphorylation of eukaryotic initiation factor 2 alpha (eIF2α) by protein kinase R-like ER kinase (PERK) plays an important role in the development and chemoresistance of pancreatic ductal adenocarcinoma (PDAC). However the expression and...
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| Veröffentlicht in: | Pancreas |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6521859/ https://ncbi.nlm.nih.gov/pubmed/30747823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000001248 |
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