Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma

Argininosuccinate synthetase 1 (ASS1), the rate-limiting enzyme for arginine biosynthesis, is expressed in many types of human malignancies. Recent studies showed that ASS1 may have tumor suppressor function and that ASS1 deficiency is associated with clinical aggressiveness in nasopharyngeal carcin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Qingqing, Stewart, John, Wang, Hua, Rashid, Asif, Zhao, Jun, Katz, Matthew H., Lee, Jeffrey E., Fleming, Jason B., Maitra, Anirban, Wolff, Robert A., Varadhachary, Gauri R., Krishnan, Sunil, Wang, Huamin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302782/
https://ncbi.nlm.nih.gov/pubmed/28187218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171985
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