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Synthesis and In Vitro Photocytotoxicity of 9-/13-Lipophilic Substituted Berberine Derivatives as Potential Anticancer Agents

The objective of this study was to synthesize the 9-/13-position substituted berberine derivatives and evaluate their cytotoxic and photocytotoxic effects against three human cancer cell lines. Among all the synthesized compounds, 9-O-dodecyl- (5e), 13-dodecyl- (6e), and 13-O-dodecyl-berberine (7e)...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Lin, Hong-Jhih, Ho, Jinn-Hsuan, Tsai, Li-Chen, Yang, Fang-Yu, Yang, Ling-Ling, Kuo, Cheng-Deng, Chen, Lih-Geeng, Liu, Yi-Wen, Wu, Jin-Yi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036939/
https://ncbi.nlm.nih.gov/pubmed/32033326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030677
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