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Development of Coumarin-Based Hydroxamates as Histone Deacetylase Inhibitors with Antitumor Activities

Histone deacetylases (HDACs) have been proved to be promising targets for the treatment of cancer, and five histone deacetylase inhibitors (HDACis) have been approved on the market for the treatment of different lymphomas. In our previous work, we designed a series of novel coumarin-containing hydro...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zhao, Na, Yang, Feifei, Han, Lina, Qu, Yuhua, Ge, Di, Zhang, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036849/
https://ncbi.nlm.nih.gov/pubmed/32046013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030717
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