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Ions Everywhere? Mg(2+) in the μ-Opioid GPCR and Atomic Details of Their Impact on Function

Filizola and co-workers have applied a combination of long-time molecular dynamics and oscillating chemical potential grand canonical Monte Carlo/molecular dynamics to investigate the distribution of Mg(2+) and Na(+) in the μ-opioid receptor and their impact on its function. Results indicate atomic...

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Vydáno v:Biophys J
Hlavní autor: MacKerell, Alexander D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036735/
https://ncbi.nlm.nih.gov/pubmed/31676136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.10.017
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