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Consensus 3D Model of μ-Opioid Receptor Ligand Efficacy based on a Quantitative Conformationally Sampled Pharmacophore
Despite being studied for over 30 years, a consensus structure-activity relationship (SAR) that encompasses the full range peptidic and non-peptidic μ opioid receptor ligands is still not available. To achieve a consensus SAR the Conformationally Sampled Pharmacophore (CSP) method was applied to dev...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113728/ https://ncbi.nlm.nih.gov/pubmed/21563754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp202542g |
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