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Evolutionarily Conserved Interactions within the Pore Domain of Acid-Sensing Ion Channels

Despite the sequence homology between acid-sensing ion channels (ASICs) and epithelial sodium channel (ENaCs), these channel families display very different functional characteristics. Whereas ASICs are gated by protons and show a relatively low degree of selectivity for sodium over potassium, ENaCs...

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Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Kasimova, Marina A., Lynagh, Timothy, Sheikh, Zeshan Pervez, Granata, Daniele, Borg, Christian Bernsen, Carnevale, Vincenzo, Pless, Stephan Alexander
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036722/
https://ncbi.nlm.nih.gov/pubmed/31630811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.09.001
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