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Blocking Substance P Signaling Reduces Musculotendinous and Dermal Fibrosis and Sensorimotor Declines in a Rat Model of Overuse Injury
Substance P-NK-1R signaling has been implicated in fibrotic tendinopathies and myositis. Blocking this signaling with a neurokinin 1 receptor antagonist (NK1RA) has been proposed as a therapeutic target for their treatment. Using a rodent model of overuse injury, we pharmacologically blocked Substan...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Connect Tissue Res |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7036028/ https://ncbi.nlm.nih.gov/pubmed/31443618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03008207.2019.1653289 |
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