Blocking Substance P Signaling Reduces Musculotendinous and Dermal Fibrosis and Sensorimotor Declines in a Rat Model of Overuse Injury

Substance P-NK-1R signaling has been implicated in fibrotic tendinopathies and myositis. Blocking this signaling with a neurokinin 1 receptor antagonist (NK1RA) has been proposed as a therapeutic target for their treatment. Using a rodent model of overuse injury, we pharmacologically blocked Substan...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Connect Tissue Res
Main Authors: Barbe, MF, Hilliard, B, Fisher, PW, White, AR, Delany, SP, Iannarone, VJ, Harris, MY, Amin, M, Cruz, GE, Popoff, SN
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036028/
https://ncbi.nlm.nih.gov/pubmed/31443618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03008207.2019.1653289
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker