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Major Histocompatibility Complex Class II-Restricted, CD4(+) T Cell-Dependent and -Independent Mechanisms Are Required for Vaccine-Induced Protective Immunity against Coxiella burnetii
To understand the role of major histocompatibility complex class I (MHC-I) and MHC-II in vaccine-mediated protection against Coxiella burnetii, we evaluated the protective efficacy of a formalin-inactivated C. burnetii Nine Mile phase I vaccine (PIV) in β(2)-microglobulin-deficient (B2m KO) and MHC-...
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| Publicado no: | Infect Immun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7035945/ https://ncbi.nlm.nih.gov/pubmed/31792078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00824-19 |
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