Both Major Histocompatibility Complex Class I (MHC-I) and MHC-II Molecules Are Required, while MHC-I Appears To Play a Critical Role in Host Defense against Primary Coxiella burnetii Infection

To understand the role of class I major histocompatibility complex (MHC-I) and class II MHC (MHC-II) antigen presentation pathways in host defense against Coxiella burnetii infection, we examined whether MHC-I or MHC-II deficiency in mice would significantly influence their susceptibility to virulen...

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Vydáno v:Infect Immun
Hlavní autoři: Buttrum, Laura, Ledbetter, Lindsey, Cherla, Rama, Zhang, Yan, Mitchell, William J., Zhang, Guoquan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865044/
https://ncbi.nlm.nih.gov/pubmed/29311245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00602-17
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