Pathways That Synthesize Phosphatidylethanolamine Impact Candida albicans Hyphal Length and Cell Wall Composition through Transcriptional and Posttranscriptional Mechanisms

Candida albicans is a leading cause of systemic bloodstream infections, and synthesis of the phospholipid phosphatidylethanolamine (PE) is required for virulence. The psd1Δ/Δ psd2Δ/Δ mutant, which cannot synthesize PE by the cytidine diphosphate diacylglycerol (CDP-DAG) pathway, is avirulent in the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Infect Immun
Prif Awduron: Tams, Robert N., Wagner, Andrew S., Jackson, Joseph W., Gann, Eric R., Sparer, Timothy E., Reynolds, Todd B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2020
Pynciau:
Fungal and Parasitic Infections
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035933/
https://ncbi.nlm.nih.gov/pubmed/31792076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00480-19
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