Candida albicans Cannot Acquire Sufficient Ethanolamine from the Host To Support Virulence in the Absence of De Novo Phosphatidylethanolamine Synthesis

Candida albicans mutants for phosphatidylserine (PS) synthase (cho1ΔΔ) and PS decarboxylase (psd1ΔΔ psd2ΔΔ) are compromised for virulence in mouse models of systemic infection and oropharyngeal candidiasis (OPC). Both of these enzymes are necessary to synthesize phosphatidylethanolamine (PE) by the...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Davis, Sarah E., Tams, Robert N., Solis, Norma V., Wagner, Andrew S., Chen, Tian, Jackson, Joseph W., Hasim, Sahar, Montedonico, Anthony E., Dinsmore, Justin, Sparer, Timothy E., Filler, Scott G., Reynolds, Todd B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056879/
https://ncbi.nlm.nih.gov/pubmed/29866908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00815-17
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi