Experimental Study of Hepatocellular Carcinoma Treatment by Shikonin Through Regulating PKM2

OBJECTIVE: Shikonin is a natural product with many activities, including anti-cancer effects. Pyruvate kinase type M2 (PKM2) plays a crucial role in the growth of tumor cells. However, the effect of shikonin on PKM2 in hepatocellular carcinoma (HCC) is unclear. METHODS: Cell viability, apoptosis lev...

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Veröffentlicht in:J Hepatocell Carcinoma
Hauptverfasser: Liu, Tong, Li, Sainan, Wu, Liwei, Yu, Qiang, Li, Jingjing, Feng, Jiao, Zhang, Jie, Chen, Jiaojiao, Zhou, Yuting, Ji, Jie, Chen, Kan, Mao, Yuqing, Wang, Fan, Dai, Weiqi, Fan, Xiaoming, Wu, Jianye, Guo, Chuanyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035901/
https://ncbi.nlm.nih.gov/pubmed/32110554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JHC.S237614
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