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PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma

BACKGROUND: The treatment for advanced primary hepatocellular carcinoma (HCC) is sorafenib (SORA), while HCC has become increasingly drug resistant with enhanced aerobic glycolysis. The present study aimed to examine the chemotherapeutic effects of a flavonoid proanthocyanidin B2 (PB2) on HCC. METHO...

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Dades bibliogràfiques
Publicat a:J Exp Clin Cancer Res
Autors principals: Feng, Jiao, Wu, Liwei, Ji, Jie, Chen, Kan, Yu, Qiang, Zhang, Jie, Chen, Jiaojiao, Mao, Yuqing, Wang, Fan, Dai, Weiqi, Xu, Ling, Wu, Jianye, Guo, Chuanyong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525465/
https://ncbi.nlm.nih.gov/pubmed/31101057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1194-z
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