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Combining microenvironment normalization strategies to improve cancer immunotherapy

Advances in immunotherapy have revolutionized the treatment of multiple cancers. Unfortunately, tumors usually have impaired blood perfusion, which limits the delivery of therapeutics and cytotoxic immune cells to tumors and also results in hypoxia—a hallmark of the abnormal tumor microenvironment (...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Mpekris, Fotios, Voutouri, Chrysovalantis, Baish, James W., Duda, Dan G., Munn, Lance L., Stylianopoulos, Triantafyllos, Jain, Rakesh K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035612/
https://ncbi.nlm.nih.gov/pubmed/32015113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1919764117
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