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Role of a DEF/Y motif in histone H2A-H2B recognition and nucleosome editing

The SWR complex edits the histone composition of nucleosomes at promoters to facilitate transcription by replacing the two nucleosomal H2A-H2B (A-B) dimers with H2A.Z-H2B (Z-B) dimers. Swc5, a subunit of SWR, binds to A-B dimers, but its role in the histone replacement reaction was unclear. In this...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Huang, Yan, Sun, Lu, Pierrakeas, Leonidas, Dai, Linchang, Pan, Lu, Luk, Ed, Zhou, Zheng
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035559/
https://ncbi.nlm.nih.gov/pubmed/32001508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914313117
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