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Thermosensitive Nucleosome Editing Reveals the Role of DNA Sequence in Targeted Histone Variant Deposition

In preparation for transcription, the chromatin remodeler SWR installs homotypic ZZ nucleosomes at promoters by replacing the two nucleosomal H2A with H2A.Z in a stepwise manner. Nucleosome-free regions (NFRs) help recruit SWR to promoters; this is thought to position SWR asymmetrically on one side...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Sun, Lu, Pierrakeas, Leonidas, Li, Tailai, Luk, Ed
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041490/
https://ncbi.nlm.nih.gov/pubmed/31914392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.12.006
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