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Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy
The exocrine pancreas expresses the highest concentrations of fibroblast growth factor 21 (FGF21) in the body, where it maintains acinar cell proteostasis. Here, we showed in both mice and humans that acute and chronic pancreatitis is associated with a loss of FGF21 expression due to activation of t...
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| Vydáno v: | Sci Transl Med |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7034981/ https://ncbi.nlm.nih.gov/pubmed/31915301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aay5186 |
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