Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis

Insulin-like growth factors (IGFs), specifically IGF1 and IGF2, promote glucose metabolism, with their availability regulated by IGF-binding proteins (IGFBPs). We hypothesized that IGF1 and IGF2 levels, or their bioavailability, are reduced during type 1 diabetes development. Total serum IGF1, IGF2,...

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Опубликовано в: :Diabetes
Главные авторы: Shapiro, Melanie R., Wasserfall, Clive H., McGrail, Sean M., Posgai, Amanda L., Bacher, Rhonda, Muir, Andrew, Haller, Michael J., Schatz, Desmond A., Wesley, Johnna D., von Herrath, Matthias, Hagopian, William A., Speake, Cate, Atkinson, Mark A., Brusko, Todd M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2020
Предметы:
Pathophysiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034187/
https://ncbi.nlm.nih.gov/pubmed/31826866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0942
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