Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis

We and others previously demonstrated that a type 1 diabetes genetic risk score (GRS) improves the ability to predict disease progression and onset in at-risk subjects with islet autoantibodies. Here, we hypothesized that GRS and islet autoantibodies, combined with age at onset and disease duration,...

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Dettagli Bibliografici
Pubblicato in:Diabetes
Autori principali: Williams, MacKenzie D., Bacher, Rhonda, Perry, Daniel J., Grace, C. Ramsey, McGrail, Kieran M., Posgai, Amanda L., Muir, Andrew, Chamala, Srikar, Haller, Michael J., Schatz, Desmond A., Brusko, Todd M., Atkinson, Mark A., Wasserfall, Clive H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2021
Soggetti:
Immunology and Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980194/
https://ncbi.nlm.nih.gov/pubmed/33419759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0937
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