Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis

Insulin-like growth factors (IGFs), specifically IGF1 and IGF2, promote glucose metabolism, with their availability regulated by IGF-binding proteins (IGFBPs). We hypothesized that IGF1 and IGF2 levels, or their bioavailability, are reduced during type 1 diabetes development. Total serum IGF1, IGF2,...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Shapiro, Melanie R., Wasserfall, Clive H., McGrail, Sean M., Posgai, Amanda L., Bacher, Rhonda, Muir, Andrew, Haller, Michael J., Schatz, Desmond A., Wesley, Johnna D., von Herrath, Matthias, Hagopian, William A., Speake, Cate, Atkinson, Mark A., Brusko, Todd M.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2020
Fag:
Pathophysiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034187/
https://ncbi.nlm.nih.gov/pubmed/31826866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0942
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