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C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors
NorA is the most studied efflux pump of Staphylococcus aureus and is responsible for high level resistance towards fluoroquinolone drugs. Although along the years many NorA efflux pump inhibitors (EPIs) have been reported, poor information is available about structure-activity relationship (SAR) aro...
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| Published in: | J Enzyme Inhib Med Chem |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7034129/ https://ncbi.nlm.nih.gov/pubmed/31992093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1719083 |
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