C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

NorA is the most studied efflux pump of Staphylococcus aureus and is responsible for high level resistance towards fluoroquinolone drugs. Although along the years many NorA efflux pump inhibitors (EPIs) have been reported, poor information is available about structure-activity relationship (SAR) aro...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Enzyme Inhib Med Chem
Autores principales: Felicetti, Tommaso, Mangiaterra, Gianmarco, Cannalire, Rolando, Cedraro, Nicholas, Pietrella, Donatella, Astolfi, Andrea, Massari, Serena, Tabarrini, Oriana, Manfroni, Giuseppe, Barreca, Maria Letizia, Cecchetti, Violetta, Biavasco, Francesca, Sabatini, Stefano
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2020
Materias:
Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034129/
https://ncbi.nlm.nih.gov/pubmed/31992093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1719083
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares