The basic residues in the Orai1 channel inner pore promote opening of the outer hydrophobic gate

Store-operated Orai1 channels regulate a wide range of cellular functions from gene expression to cell proliferation. Previous studies have shown that gating of Orai1 channels is regulated by the outer pore residues V102 and F99, which together function as a hydrophobic gate to block ion conduction...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Gen Physiol
Main Authors: Yamashita, Megumi, Ing, Christopher E., Yeung, Priscilla See-Wai, Maneshi, Mohammad M., Pomès, Régis, Prakriya, Murali
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034092/
https://ncbi.nlm.nih.gov/pubmed/31816637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912397
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker