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Effect of verapamil on the pharmacokinetics of hydroxycamptothecin and its potential mechanism
CONTEXT: Hydroxycamptothecin (HCPT) has antitumor activity in various cancers, but its poor bioavailability and efflux limit its clinical application. Verapamil has been demonstrated to improve the bioavailability of many drugs. However, the effect of verapamil on the pharmacokinetics of HCPT was no...
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| Publicado no: | Pharm Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7034088/ https://ncbi.nlm.nih.gov/pubmed/31990625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2020.1717550 |
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