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The Methyl-CpG-Binding Protein Mbd2 Regulates Susceptibility to Experimental Colitis via Control of CD11c(+) Cells and Colonic Epithelium

Methyl-CpG-binding domain-2 (Mbd2) acts as an epigenetic regulator of gene expression, by linking DNA methylation to repressive chromatin structure. Although Mbd2 is widely expressed in gastrointestinal immune cells and is implicated in regulating intestinal cancer, anti-helminth responses and colon...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: Jones, Gareth-Rhys, Brown, Sheila L., Phythian-Adams, Alexander T., Ivens, Alasdair C., Cook, Peter C., MacDonald, Andrew S.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033935/
https://ncbi.nlm.nih.gov/pubmed/32117307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00183
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