Peripheral inflammation promotes brain tau transmission via disrupting blood–brain barrier

Abnormal aggregation of pathological tau protein is a neuropathological feature of Alzheimer’s disease (AD). In the AD patients, the abnormal tau accumulation first appeared in entorhinal cortex (EC) and then propagated to the hippocampus with microglia activation and inflammation, but the mechanism...

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Podrobná bibliografie
Vydáno v:Biosci Rep
Hlavní autoři: Liu, Yanchao, Zhang, Shujuan, Li, Xiaoguang, Liu, Enjie, Wang, Xin, Zhou, Qiuzhi, Ye, Jinwang, Wang, Jian-Zhi
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2020
Témata:
Aging
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033313/
https://ncbi.nlm.nih.gov/pubmed/32043530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20193629
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