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Peripheral inflammation promotes brain tau transmission via disrupting blood–brain barrier
Abnormal aggregation of pathological tau protein is a neuropathological feature of Alzheimer’s disease (AD). In the AD patients, the abnormal tau accumulation first appeared in entorhinal cortex (EC) and then propagated to the hippocampus with microglia activation and inflammation, but the mechanism...
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| Опубликовано в: : | Biosci Rep |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Portland Press Ltd.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7033313/ https://ncbi.nlm.nih.gov/pubmed/32043530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20193629 |
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