Peripheral inflammation promotes brain tau transmission via disrupting blood–brain barrier

Abnormal aggregation of pathological tau protein is a neuropathological feature of Alzheimer’s disease (AD). In the AD patients, the abnormal tau accumulation first appeared in entorhinal cortex (EC) and then propagated to the hippocampus with microglia activation and inflammation, but the mechanism...

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Dades bibliogràfiques
Publicat a:Biosci Rep
Autors principals: Liu, Yanchao, Zhang, Shujuan, Li, Xiaoguang, Liu, Enjie, Wang, Xin, Zhou, Qiuzhi, Ye, Jinwang, Wang, Jian-Zhi
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2020
Matèries:
Aging
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033313/
https://ncbi.nlm.nih.gov/pubmed/32043530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20193629
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