IgG-Fc glycosylation before and after rituximab treatment in immune thrombocytopenia

The interactions of antibodies with myeloid Fcγ receptors and the complement system are regulated by an Asn297-linked glycan in the Fc portion of IgG. Alterations of serum IgG-Fc glycosylation have been reported in various autoimmune diseases, and correlate with treatment response and disease activi...

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Publicat a:Sci Rep
Autors principals: Schmidt, David E., de Haan, Noortje, Sonneveld, Myrthe E., Porcelijn, Leendert, van der Schoot, C. Ellen, de Haas, Masja, Zwaginga, Jaap-Jan, Wuhrer, Manfred, Vidarsson, Gestur
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033207/
https://ncbi.nlm.nih.gov/pubmed/32080262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59651-7
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